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Panorama NIPT (10-40 Weeks)

  •  Appointments available every day, including evening and weekends
  •  Detailed ultrasound scan included by our Advanced Sonographer
  •  Result in 7 - 14 calendar days.
  •  Can be performed from 10 weeks
  •  Electronic transmission of scan to your email via YourBabyScan
  •  Optional sex determination included in the price

 

What is the Panorama test?

It has been discovered that a blood sample taken from the mother at any time from 10 weeks of pregnancy can be analysed for cell free fetal DNA, which is essentially a marker in the mother’s blood of the DNA of the baby. The result of the simple blood test (Panorama NIPT) has a high detection rate for Down’s syndrome, Edwards syndrome and Patau’s syndrome, which may reduce the need for unnecessary invasive testing by CVS or amniocentesis. It can also be used to detect other chromosomal abnormalities such as Triploidy.

This is great news for expectant couples. It is important that an ultrasound scan is performed just before the blood test to confirm the pregnancy. The Panorama Test can also be performed for twin pregnancies.

The Panorama Test is not available for Vanishing twin, multiple gestation of more than 2 fetuses, or twins conceived using an egg donor or surrogate. 

Why the Panorama test?

The Panorama is the most preferred NIPT for patients visiting The Birth Company. For the last ten years doctors have been using the results of the Nuchal Translucency Scan to advise pregnant women and their partners on their probability of having a baby with a chromosomal abnormality such as Down syndrome, or other abnormalities (Edwards and Pataus). The Nuchal Translucency Scan looks at the skin fold on the back of the baby’s neck at about 12 weeks. This has been further refined by looking at the nose bone of the baby with an additional blood test to identify two pregnancy hormones. This is the combined test and has achieved a predictive value of about 84% for Downs syndrome. Women with a high probability have an option to proceed to chorion villous sampling (CVS) or amniocentesis. These are invasive tests that carry a miscarriage risk of about 1:100. 

Who needs the Panorama Test?

Panorama is the test of preference for most patients visiting The Birth Company. Couples who wants extra reassurance about their pregnancy can have the test. Women who may need it are those who are anxious about their baby having a chromosomal abnormality such as Downs, Edwards or Patau's syndrome, Older women (particularly over 40 years) and those who have already had a chromosomally abnormal pregnancy often opt for the test. Those who are at particular risk of miscarriage should they have an amniocentesis or chorionic villous sample.

How is the test done?

  • The mother has to read and sign a consent form.
  • An ultrasound scan is always performed first.
  • This is a simple blood test from the vein in the woman's arm like any other blood test. There is no risk from having the test.
  • Two blood tubes need to be collected.
  • The blood tubes are immediately packaged and sent to the USA.

How long does it take to get a result?

The result is usually available within 7-14 calendar days. There is a 4% chance that no result is obtained. If the test is unsuccessful, an offer of a repeat test is made free of charge. We understand it can be a stressful time waiting for results and we will endeavour to communicate any delays to our patients as soon as we receive information from the laboratory.

How is the result expressed?

The result is expressed as a probability. This is not a positive or negative test: It is a screening test and not a diagnostic test. An example of a low probability test is shown below. A low probability test result gives a probability of a chromosomal problem of less than 1:10000. A high probability result does not confirm that the baby has the chromosome abnormality. An amniocentesis or chorionic villous sampling is necessary to give a diagnosis. Genetic counselling is recommended in the case of a high probability. 

> Panorama Natera Consent forms 22Q

> Panorama Natera Consent forms Aneuploid Only

> Panorama Natera Consent forms Full MicroD

> Example 1 Panorama NIPT Low probability sample report

> Example 2 Panorama NIPT High probability sample report

> Panorama FAQ

How much does it cost?

The Panorama Test is £500.
Included with every NIPT is an ultrasound by one of our Advanced Sonographers.
Appointments after 5pm, weekends and bank holidays incur a £50 surcharge.
NIPT appointments with the Consultant incur an additional charge of £150. Please note Dr Gibb is available on Thursday afternoons.
 

What happens after the test?

Depending on how many weeks pregnant you are, we recommend you take the opportunity to have a 12 week scan privately or with the NHS. The focus of the 12 week scan will change as you will already have the result of the Downs syndrome test, so the 12 week scan will look at the baby in detail for structural abnormalities (these may exist without a chromosomal abnormality). The next routine ultrasound scan performed privately, or within the NHS, is the 20 week Anomaly scan. If the Panorama Test is low probability then it is important that the person conducting the 12 week scan is aware of this. If the test is high probability then you should return to The Birth Company or your NHS unit for further counselling.

Many patients choose to upgrade to the comprehensive Gold Package - Click Here for more details.

Are there problems this test will not detect?

Yes. Structural abnormalities such as abnormal limbs, spina bifida, heart defects and a poorly growing baby will only be demonstrated on ultrasound scans, often not until the second and third trimester. 

This new test has been developed by Natera Inc., San Carlos, California.

 

Please note in the circumstance that during your appointment an ultrasound scan is performed but we do not proceed to the NIPT, a fee of £120 (£180 for evening/weekend appointments) will be charged for the appointment only. If booked online, £380 will be refunded to you

Please note Anticoagulation therapy (commonly known as blood thinners) can increase the possibility of receiving No Result for your NIPT. Please leave as long between administering your dose and your NIPT appointment as possible. For example, if you administer in the evening and have an early morning appointment, either change to an appointment late in the day, or refrain from your evening dose. If you administer in the morning, refrain from that dose until after your appointment. If you have any queries regarding this, please contact our team admin@thebirthcompany.co.uk.

For further information please see below:
Anticoagulation Therapy Publication

 


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THE BIRTH COMPANY - LONDON

137 Harley Street, London W1G 6BF
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Great Portland Street

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Alderley Edge Medical Centre, Talbot Road, Alderley Edge, Cheshire, SK9 7HR
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Alderley Edge