Panorama NIPT (10-40 Weeks)

  • Appointments every day including Sunday.
  • Electronic transmission of scan to your email by Tricefy.
  • Ultrasound scan included.
  • Result in 7-14 calendar days.
  • Optional sex determination included in the price


What is the Panorama test?

It has been discovered that a blood sample taken from the mother at any time from 10 weeks of pregnancy can be analysed for cell free fetal DNA, which is essentially a marker in the mother’s blood of the DNA of the baby. The result of the simple blood test (Panorama) has a detection rate of more than 99% in Down’s syndrome, Edwards syndrome and Patau’s syndrome, which will hugely reduce the need for invasive testing by CVS or amniocentesis. It can also be used to detect other chromosomal abnormalities such as Turners syndrome and Triploidy and has a detection rate of more than 92%.

This is great news for couples because it eliminates the risk of miscarriage of the pregnancy. It is important that an ultrasound scan is performed just before the blood test to confirm the pregnancy. The Panorama Test is not available for Vanishing twin, multiple gestation of more than 2 fetuses, or twins conceived using an egg donor or surrogate. The result of the Panorama has a detection rate of more than 99%.

Why the Panorama test?

For the last ten years doctors have been using the results of the Nuchal Translucency Scan to advise pregnant women and their partners on their risk of having a baby with a chromosomal abnormality such as Down syndrome, or other abnormalities (Edwards, Patau’s, Turners syndrome and Triploidy). The Nuchal Translucency Scan looks at the skin fold on the back of the baby’s neck at about 12 weeks. This has been further refined by looking at the nose bone of the baby with an additional blood test to identify two pregnancy hormones. This is the combined test and has achieved a predictive value of about 84% for Downs syndrome. Women with a high risk have an option to proceed to chorion villous sampling (CVS) or amniocentesis. These are invasive tests that carry a miscarriage risk of about 1:100. This is changing. Microdeletions are avaialable with Panorama.


This test is done to look for several rare but serious conditions which are not related to maternal age. In our patients 97 out of 100 cases get a reassuring low risk result. However there is a possibility there will be no result in about 2 in 100. There is a 1 in 100 chance that there will be a high risk result for Microdeletions. Remember that in this case there will already be a low risk for Down’s syndrome. A high risk result will cause anxiety and indeed it may lead to a decision for an invasive test such as amniocentesis or chronic villous sample. The chance of such a test confirming that the child is affected or indeed the child being born with the condition is only 1 in 20. The quantity fetal fraction detected in the blood sample affects the detection rate for microdeletion screening.

> Microdeletion information

Who needs the Panorama Test?

Anyone who wants extra reassurance about their pregnancy can have the test. Women who may need it are those who are anxious about their baby having a chromosomal abnormality such as Downs, Edwards or Patau's syndrome, Older women (particularly over 40 years) and those who have already had a chromosomally abnormal pregnancy often opt for the test. Those who are at particular risk of miscarriage should they have an amniocentesis or chorionic villous sample, also find the test very attractive as it avoids an invasive procedure. It is helpful for those who have had a previous sex chromosome abnormality such as Turners syndrome. Analysis of Microdeletions is particularly uselful for women of any age concerned about this issue. When a fetus has a heart defect or is not growing well this may be clinically indicated.

How is the test done?

  • The mother has to read and sign a consent form and sign a form for data release.
  • An ultrasound scan is always done first.
  • This is a simple blood test from the vein in the woman's arm like any other blood test. There is no risk from having the test.
  • Two tubes need to be fully filled.
  • The tubes are immediately packaged and sent to the USA.

How long does it take to get a result?

The result is usually available within 7-14 calendar days. There is a 4% chance that no result is obtained. This is not a positive or negative test: it is an unsuccessful test. An offer of a repeat test is made free of charge. This is usually successful. In rare circumstances the result can take longer than 14 days. We understand it can be a stressful time waiting for results and we will endevour to communicate any delays to our patients as soon as we receive information from the laboratory.

How is the result expressed?

The result is expressed as a probability. It is a screening test and not a diagnostic test. A result form of a low risk test is shown below. A low risk test result gives a risk of a chromosomal problem of less than 1:10000. A high risk result gives a risk of greater than 99%. A high risk result does not confirm that the baby has the chromosome abnormality. An amniocentesis or chorionic villous sampling is necessary to give a diagnosis. The couple are counselled about this.

Panorama Natera Consent forms 22Q

Panorama Natera Consent forms Aneuploid Only

Panorama Natera Consent forms Full MicroD

> Example 1 Panorama NIPT Low risk sample report

> Example 2 Panorama NIPT High risk sample report

> Panorama FAQ

How much does it cost?

The Panorama Test is £500. If you would like to add Microdeletions the cost will be £680.
Appointments after 5pm, weekends and bank holidays incur a £50 surcharge.
Included with every NIPT is an ultrasound by one of our advanced sonographers.

What happens after the test?

Depending on how many weeks pregnant you are, you will still have the opportunity to have a 12 week scan privately or with the NHS. The focus of the 12 week scan will change as you will already have the result of the Downs syndrome test, so the 12 week scan will look at the baby in detail for structural abnormalities (these may exist without a chromosomal abnormality). You will still have the opportunity to have the later scans, such as the 20 weeks scan, as before. If the Panorama test is low risk then it is important that the person conducting the 12 week scan is aware of this. If the test is high risk then you should return to The Birth Company or a good NHS unit for further counselling.

Are there problems this test will not detect?

Yes. Structural abnormalities such as abnormal limbs, spina bifida, heart defects and a poorly growing baby will only be seen on scans and sometimes not until later scans. These scans should still be undertaken.

This new test has been developed by Natera Inc., San Carlos, California.


Please note in the circumstance that during your appointment an ultrasound scan is performed but we do not proceed to the NIPT, a fee of £100 (£150 for evening/weekend appointments) will be charged for the appointment only. If booked online, £400 will be refunded to you.

Please note Anticoagulation therapy (blood thinners such as Clexane) can increase the possibility of receiving No Result for your NIPT. Please leave as long between administering your dose and your NIPT appointment as possible. For example, if you administer in the evening and have an early morning appointment, either change to an appointment late in the day, or refrain from your evening dose. If you administer in the morning, refrain from that dose until after your appointment. If you have any queries regarding this, please contact our team

For further information please see below:
Anticoagulation Therapy Publication


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